Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture

    March 2024 in “ Journal of functional foods ”
    Karin I. Pappelbaum, Nicolina Virgilio, Lisa Epping … Marta Bertolini
    Studysummary This study found that both marine and bovine collagen peptides may help prevent hair loss by supporting epithelial hair follicle stem cell functions, with marine peptides maintaining hair in the growth phase and bovine peptides increasing stem cell presence in hair follicle regions.
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    Research cited in this study 38

    1. Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration 2024
    2. Effects of Oxytocin on the Hair Growth Ability of Dermal Papilla Cells Scientific Reports · 2023
    3. Efficacy and Tolerability of an Oral Supplement Containing Amino Acids, Iron, Selenium, and Marine Hydrolyzed Collagen in Subjects With Hair Loss: A Prospective, Randomized, 3-Month, Controlled, Assessor-Blinded Study Skin Research and Technology · 2023
    4. Effect of Plantago Asiatica L. Extract on the Anagen Phase in Human Hair Follicle Dermal Papilla Cells Journal of Cosmetic Dermatology · 2023
    5. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    6. Effective And Economical Cell Therapy For Hair Regeneration Biomedicine & Pharmacotherapy · 2022
    7. Intermediate Hair Follicles from Patients with Female Pattern Hair Loss Are Associated with Nutrient Insufficiency and a Quiescent Metabolic Phenotype Nutrients · 2022
    8. An Extract of Leontopodium Alpinum Inhibits Catagen Development Ex Vivo and Increases Hair Density In Vivo International Journal of Cosmetic Science · 2022
    9. Targeted Nutritional Supplementation for Telogen Effluvium: Multicenter Study on Efficacy of a Hydrolyzed Collagen, Vitamin, and Mineral-Based Induction and Maintenance Treatment International Journal of Trichology · 2022
    10. Observations Suggesting a Contribution of Altered Dermal Papilla Mitochondrial Function to Androgenetic Alopecia Experimental Dermatology · 2022
    11. Systematic Review: The Platelet-Rich Plasma Use in Female Androgenetic Alopecia as Effective Autologous Treatment of Regenerative Plastic Surgery Journal of Plastic Reconstructive and Aesthetic Surgery · 2021
    12. Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells Clinical, Cosmetic and Investigational Dermatology · 2021
    13. Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis The EMBO Journal · 2021
    14. Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients Journal of Dermatological Science · 2020
    15. Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters Journal of Cosmetic Dermatology · 2020
    16. The Oral Intake of Specific Bioactive Collagen Peptides Has a Positive Effect on Hair Thickness Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods · 2020
    17. Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration Journal of Biomedical Science · 2020
    18. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    19. Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential Experimental Dermatology · 2019
    20. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    21. A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth Experimental Dermatology · 2018
    22. Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2 Scientific Reports · 2017
    23. Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016
    24. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    25. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    26. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    27. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    28. Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges BioEssays · 2014
    29. Beta-1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis, and Migration of Their Progeny PLoS ONE · 2013
    30. Nutrition and Hair: The Role of Nutrients in Hair Health Dermatologic Clinics · 2012
    31. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    32. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    33. Hair Follicle Neogenesis Induced by Cultured Human Scalp Dermal Papilla Cells Regenerative Medicine · 2009
    34. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    35. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    36. Dissecting the Impact of Chemotherapy on the Human Hair Follicle ˜The œAmerican journal of pathology · 2007
    37. Stem Cells and Their Niches Science · 2006
    38. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003

    Related research 7

    1. Hair Loss (Alopecia or Baldness) 2018
    2. Treatments of Hereditary Hair Loss (Alopecia) 2018
    3. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
    4. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    5. Reorganization of Hair Follicles in Human Skin Organ Culture Induced by Cultured Human Follicle-Derived Cells Experimental Dermatology · 2005
    6. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    7. Treatment of Hair Loss The New England Journal of Medicine · 1999