Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients

    November 2020 in “ Journal of Dermatological Science ”
    Parvaneh Mohammadi, Mohammad Ali Nilforoushzadeh, Khalil Kass Youssef … Nasser Aghdami
    Studysummary In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.
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    Research cited in this study 14

    1. An Analysis of Gene Expression Data Involving Examination of Signaling Pathways Activation Reveals New Insights into the Mechanism of Action of Minoxidil Topical Foam in Men with Androgenetic Alopecia Cell Cycle · 2017
    2. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    3. TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles Laboratory Investigation · 2016
    4. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
    5. Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22 PLOS Genetics · 2015
    6. Hairless Up-Regulates TGF-β2 Expression via Down-Regulation of miR-31 in the Skin of Hairpoor (HrHp) Mice Journal of cellular physiology · 2015
    7. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
    8. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    9. Differential Response of Epithelial Stem Cell Populations in Hair Follicles to TGF-Beta Signaling Developmental Biology · 2012
    10. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    11. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    12. Male Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2010
    13. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    14. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro Journal of Investigative Dermatology · 1998