Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients

January 2021 in “ Journal of Dermatological Science ”

Parvaneh Mohammadi, Mohammad Ali Nilforoushzadeh, Khalil Kass Youssef, Ali Sharifi-Zarchi, Sharif Moradi, Pardis Khosravani, Raheleh Aghdami, Payam Taheri, Ghasem Hosseini Salekdeh, Hossein Baharvand, Nasser Aghdami

microRNA hair follicular stem cells progenitor cells androgenic alopecia miR-324-3p hair follicle size reduction differentiation hair loss hair stem cells hair progenitor cells male pattern baldness

TLDR Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.

This study identified microRNA signatures in hair follicular stem and progenitor cells of healthy individuals and those with androgenic alopecia. The study found significant differences in microRNA expression between the two groups, suggesting potential targets for future treatments of this condition. The researchers identified miR-324-3p as a potential treatment target for androgenic alopecia by affecting hair follicle size reduction and differentiation.

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