MicroRNAs and Their Regulatory Interactions in the Human Hair Follicle

The study from September 2016 investigated the role of microRNAs (miRNAs) in human hair follicle biology by analyzing the expression and regulatory interactions of 9 miRNAs in samples from 25 healthy male donors. The researchers confirmed the expression of 7 miRNAs and found significant correlations between the levels of 3 miRNAs (miR-24, miR-31, miR-106a) and their target genes, which are involved in hair biology. They also identified an enrichment of target genes in pathways relevant to hair growth and confirmed protein-protein interactions among the gene products. These findings enhance the understanding of miRNAs in hair follicle function and may have implications for hair growth and alopecia.