10 citations
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May 2020 in “Frontiers in cell and developmental biology” In this study, researchers found that Dicer, but not Tarbp2, plays a crucial role in regulating the growth phase of hair follicles in post-natal mice.
January 2012 in “ScholarlyCommons (University of Pennsylvania)” This study found that miRNA biogenesis, facilitated by Dicer and Drosha, is crucial for adult hair follicles' growth and regeneration, highlighting their multiple roles during the hair follicle growth cycle.
82 citations
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March 2012 in “Development” This study found that deleting the miRNA processing enzymes Drosha and Dicer from mouse skin epithelial cells disrupted normal hair follicle development and maintenance, leading to follicular degradation and stem cell loss during the growth phase.
January 2010 in “Bradford Scholars (University of Bradford)” This study found that microRNAs play key roles in regulating gene expression during the hair cycle in mice, impacting follicle growth and skin homeostasis through mechanisms involving major signalling pathways.
13 citations
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June 2020 in “BMC genomics” This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.