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    GlossaryPost-Transcriptional Gene Silencing

    cells inhibit gene expression after RNA is made

    Post-Transcriptional Gene Silencing (PTGS) is a cellular process where the expression of specific genes is inhibited after the DNA has been transcribed into RNA. This is often achieved through mechanisms like RNA interference (RNAi), where small RNA molecules bind to the messenger RNA (mRNA) and prevent it from being translated into proteins. This process is crucial for regulating gene expression and maintaining cellular function.

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      technique to create small wounds in skin to activate collagen production and hair growth

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      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Adrogens and Covid-19

      in Treatment  7 upvotes 4 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  37 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.