Beta-1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis, and Migration of Their Progeny

December 2013 in “ PLoS ONE ”

Nancy Ernst, Arzu Yay, Tamás Bı́ró, Stephan Tiede, Martin J. Humphries, Ralf Paus, Jennifer E. Kloepper

β1 integrin epithelial progenitor cells cell proliferation apoptosis cell migration tissue homeostasis tissue repair

Studysummary This study found that β1 integrin-mediated signaling is crucial for the survival, adhesion, and migration of epithelial progenitor cells in human scalp hair follicles, with varying responses observed among cell subpopulations.

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