Image

    Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling

    June 2003 in “ ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings ”
    Vladimir A. Botchkarev, Jiro Kishimoto
    Studysummary This article reviews the role of epithelial-mesenchymal interactions in hair follicle morphogenesis and the hair cycle, suggesting potential paths for developing treatments for hair growth disorders but providing no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jidsponline.org →
    Discuss this study in the Community →

    Research cited in this study 53

    1. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    2. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002
    3. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    4. Interferon Beta Secreted from Human Hair Dermal Papilla Cells Inhibits the Growth of Outer Root Sheath Cells Cultured in Vitro Biochemical and biophysical research communications · 2002
    5. Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla Journal of Investigative Dermatology · 2001
    6. Keratin K6irs Is Specific to the Inner Root Sheath of Hair Follicles in Mice and Humans British Journal of Dermatology · 2001
    7. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001
    8. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    9. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    10. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    11. Metabolic And Cellular Analysis Of Alopecia In Vitamin D Receptor Knockout Mice Journal of Clinical Investigation · 2001
    12. Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    13. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    14. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    15. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000
    16. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000
    17. Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs Genomics · 2000
    18. 17β-Estradiol and ICI-182780 Regulate the Hair Follicle Cycle in Mice Through an Estrogen Receptor-α Pathway Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism · 2000
    19. Whn and mHa3 Are Components of the Genetic Hierarchy Controlling Hair Follicle Differentiation Mechanisms of Development · 1999
    20. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    21. Insulin-Like Growth Factor 1 and Hair Growth Dermatology Online Journal · 1999
    22. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    23. The Mouse Keratin 6 Isoforms Are Differentially Expressed in the Hair Follicle, Footpad, Tongue, and Activated Epidermis Differentiation · 1999
    24. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    25. The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen Journal of Investigative Dermatology · 1999
    26. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    27. Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2 Journal of Investigative Dermatology · 1999
    28. The Role of the Hairless (Hr) Gene in the Regulation of Hair Follicle Catagen Transformation American Journal Of Pathology · 1999
    29. Expression of Vascular Endothelial Growth Factor (VEGF) in Various Compartments of the Human Hair Follicle Archives of Dermatological Research · 1998
    30. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro Journal of Investigative Dermatology · 1998
    31. Basonuclin as a Cell Marker in the Formation and Cycling of the Murine Hair Follicle Differentiation · 1998
    32. Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans Experimental Dermatology · 1998
    33. Towards Defining the Pathogenesis of the Hairless Phenotype Journal of Investigative Dermatology · 1998
    34. 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla Archives of Dermatological Research · 1998
    35. Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    36. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    37. Hoxc13 Mutant Mice Lack External Hair Genes & Development · 1998
    38. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    39. Expression of Retinoid Nuclear Receptor Superfamily Members in Human Hair Follicles and Its Implication in Hair Growth Acta Dermato Venereologica · 1997
    40. Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture Journal of interferon & cytokine research · 1997
    41. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    42. Human Hair Follicle Dermal Papilla Cell, Dermal Sheath Cell, and Interstitial Dermal Fibroblast Characteristics PubMed · 1996
    43. Regulation of Human Dermal Papilla Cell Production of Insulin-Like Growth Factor Binding Protein-3 by Retinoic Acid, Glucocorticoids, and Insulin-Like Growth Factor-1 Journal of cellular physiology · 1996
    44. Message of Nexin 1, a Serine Protease Inhibitor, Accumulates in the Follicular Papilla During Anagen of the Hair Cycle Journal of Cell Science · 1995
    45. Expression of the Bcl-2 Proto-Oncogene in the Cycling Adult Mouse Hair Follicle Journal of Investigative Dermatology · 1994
    46. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994
    47. Hair Follicle Proteoglycans Journal of Investigative Dermatology · 1993
    48. Changes in Fibronectin, Laminin, and Type IV Collagen Distribution Relate to Basement Membrane Restructuring During the Rat Vibrissa Follicle Hair Growth Cycle PubMed · 1992
    49. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
    50. The Secret Life of the Hair Follicle Trends in genetics · 1992
    51. Rat Hair Follicle Dermal Papillae Have an Extracellular Matrix Containing Basement Membrane Components Journal of Investigative Dermatology · 1986
    52. Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle Journal of Investigative Dermatology · 1984
    53. Morphogenesis of the Hair Follicle During Catagen Cell and Tissue Research · 1970

    Related research 6

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    4. Interrogating the Integument: The Role of the Epidermis in Hair Induction Experimental dermatology · 2014
    5. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    6. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006