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This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.

This study found that the heat shock cognate protein Hsc70 was differentially expressed by dihydrotestosterone treatment in SV40-transformed dermal papilla cells, suggesting its involvement in androgen action on these cells.

This study successfully established an immortalized human dermal papilla cell line that maintains characteristics of original cells without malignant transformation, potentially benefiting hair research.

Researchers made a cell line that grows quickly and can help with hair growth research.

In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.

In this study, researchers successfully established immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia patients, observing distinct gene expression, androgen receptor levels, and hair follicle growth effects between these regions, which may help advance hair loss research and therapeutic development.

This study suggests that an extract from Malva verticillata seeds could help treat hair loss by modulating the Wnt/β-catenin pathway in cultured human dermal papilla cells.

This study identified three genes with significantly higher expression in androgen-sensitive beard dermal papilla cells compared to androgen-insensitive scalp cells, suggesting potential novel signaling pathways in hair follicles.

This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.

This study found that altering levels of SFRP1 in human dermal papilla cells affects cell function and regulates Wnt/β-catenin signaling or telomerase activity, suggesting that targeting SFRP1 could potentially offer a new approach to treat hair loss diseases.

The researchers reported that marine-derived saccharides, specifically L-fucose and chondroitin sulphate disaccharide, supported skin and hair health by promoting cellular proliferation, enhancing extracellular matrix production, and aiding the hair cycle's growth phase, potentially minimizing aging effects.

This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.

This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which is suitable for research and application.

This study suggests that apigenin may stimulate hair growth by downregulating TGF-ß1 gene expression in human epidermal keratinocytes and promoting hair follicle elongation in a rat hair follicle culture.

In this study, 7-phloroeckol, derived from marine brown algae, was found to promote hair growth by increasing cell proliferation and hair shaft elongation in cultured human hair follicles.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.

This study found that berry extracts, especially black raspberry extract, may have anti-aging effects due to their high antioxidant activities.

This study developed immortalized cell-based models to screen and evaluate potential hair-care materials by forming hair follicle-like structures that respond to hair growth-promoting compounds.

This study reports the successful generation of inducible pluripotent stem cells from mesenchymal stem cells derived from human hair follicles, marking a novel method of reprogramming these cells.

This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.

This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.

This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.

In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.

In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.

This review evaluates laboratory models used in androgenetic alopecia research but reports no new findings, emphasizing the potential of human-derived 3-D models for future studies.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.

This study identified a subpopulation of neural crest-derived progenitor cells in human corneal endothelial tissue from normal and Fuchs endothelial corneal dystrophy donors, which may have potential for future cell therapy development.

This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.

In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.