Existence of Neural Crest-Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium

    September 2016 in “ American Journal Of Pathology ”
    Kishore Reddy Katikireddy, Thore Schmedt, Marianne O. Price … Ula V. Jurkunas
    Studysummary This study identified a subpopulation of neural crest-derived progenitor cells in human corneal endothelial tissue from normal and Fuchs endothelial corneal dystrophy donors, which may have potential for future cell therapy development.
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    Research cited in this study 2

    1. Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways Stem cells · 2013
    2. Constitutive Internalization of the Leucine-Rich G Protein-Coupled Receptor-5 (LGR5) to the Trans-Golgi Network Journal of Biological Chemistry · 2013