Establishment and Identification of Immortalized Sheep Ovarian Granulosa Cells

    September 2025
    Hao Chen, Zhijie Zhao, Xianzhong Ding, P. Andy Li, Bingzhu Zhao, Yue Yuan, Rui Xiao, Taojie Zhang, Yingpai Zhaxi, Shengdong Huo
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    Studysummary This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
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