Understanding the Molecular Basis of Mesenchymal Stem Cell Stemness: Implications for Clinical Applications

    November 2025 in “ Cell Death and Disease ”
    Tongming Liu, William P. Tew, Zheng Yang … Simon M. Cool
    Studysummary This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.
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    Research cited in this study 1

    1. OCT4 Maintains Self-Renewal and Reverses Senescence in Human Hair Follicle Mesenchymal Stem Cells Through the Downregulation of p21 by DNA Methyltransferases Stem Cell Research & Therapy · 2019