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    Glossary Epigenetic Regulation

    chemical modifications that turn genes on or off

    Epigenetic Regulation refers to the process by which genes are turned on or off without changing the underlying DNA sequence. This is achieved through chemical modifications, such as DNA methylation and histone modification, which can influence gene expression and, consequently, cellular function. These changes can be influenced by environmental factors and can be heritable, playing a crucial role in development, disease, and adaptation.

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    1. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    2. Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury Clinical Epigenetics · 2024 · 13 citations
    3. Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing BMC Biology · 2022 · 8 citations
    4. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    5. Epigenetic regulations on skin wound healing: implications from current researches. PubMed · 2015 · 5 citations
    6. Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells Cell stem cell · 2011 · 5 citations
    7. Epigenetic Regulation of Medulloblastoma Proliferation by Finasteride-Induced Modulation of BTG2 and CD244 Gene Methylation 2023
    8. Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases 2017 · 2 citations
    9. Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT ‐ qPCR Validation The FASEB Journal · 2026
    10. 651 Epigenetic regulation of macrophage activity by glutamine during wound healing Journal of Investigative Dermatology · 2024
    11. Epigenetic and Environmental Regulation of Skin Appendage Regeneration 2015
    12. Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets. PubMed · 2016 · 39 citations
    13. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    14. Advances in understanding epigenetic regulation of plant trichome development: a comprehensive review Horticulture research · 2023 · 1 citations
    15. Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo PLoS ONE · 2025
    16. INVESTIGATIONS INTO THE ROLE OF THE X-LINKED EPIGENETIC REGULATOR UTX (KDM6A) IN SELF-RENEWING STRATIFYING EPITHELIA Scholarly Commons (University of Pennsylvania) · 2025
    17. Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology · 2021 · 36 citations
    18. Epigenetic control of skin and hair regeneration after wounding Experimental Dermatology · 2014 · 36 citations
    19. Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People Biomedicines · 2022 · 9 citations
    20. Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation Journal of Cutaneous Pathology · 2019 · 4 citations
    21. Epigenetic mechanism of Gtl2-miRNAs causes the primitive sheep characteristics found in purebred Merino sheep Cell & bioscience · 2023
    22. Epigenetic Effects of Finasteride on Dopaminergic Signaling Pathways: A potential contributor to Post-Finasteride Syndrome Physiology · 2024
    23. Regulation of somatic cell reprogramming through inducible mir-302 expression Nucleic acids research · 2010 · 308 citations
    24. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    25. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    26. Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction Endocrinology · 2012 · 44 citations
    27. A primer for studying cell cycle dynamics of the human hair follicle Experimental Dermatology · 2016 · 38 citations
    28. Keratinocyte biology and pathology Veterinary Dermatology · 2014 · 33 citations
    29. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    30. LSD1 is Required for Hair Cell Regeneration in Zebrafish Molecular Neurobiology · 2015 · 28 citations