TLDR BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
The study investigated the BMP4 gene in Liaoning cashmere goats, focusing on its role in hair follicle development and cycle. Researchers found that the BMP4 cDNA was 1264-bp long, encoding a 409 amino acid precursor peptide. BMP4 transcription increased from anagen to telogen stages, and higher methylation levels in the 5′ flanking regulatory region were linked to lower BMP4 mRNA expression. These results highlighted BMP4's significant role in hair follicle development and its epigenetic regulation in these goats.
6 citations,
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August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
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61 citations,
April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
