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GlossaryDNA methylation

chemical modification of DNA that can regulate gene expression

DNA methylation is a biological process where a methyl group is added to the DNA molecule, typically at cytosine bases. This modification can change the activity of a DNA segment without altering the sequence, often leading to gene silencing. It's a crucial mechanism in regulating gene expression and is involved in various processes, including development, aging, and disease.

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research Independent Genomewide Screens Identify the Tumor Suppressor VTRNA2-1 as a Human Epiallele Responsive to Periconceptional Environment

153 citations , June 2015 in “GenomeBiology.com”

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

research Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat

20 citations , January 2017 in “Genetica”

The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.

research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle

18 citations , July 2016 in “Genetica”

BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.

research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study

8 citations , July 2019 in “Endocrine connections”

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

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community Used finasteride 10 years ago and I still suffer from severe ED. I have blood test results attached

in Finasteride 10 upvotes 7 years ago

A user took finasteride for hair loss 10 years ago, stopped after a month, and has since suffered from severe erectile dysfunction (ED) and other symptoms. They shared blood test results seeking advice for their condition, and others discussed similar experiences with finasteride and related drugs.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 2 years ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community Did anyone see a difference in hair growth after correcting a folic acid (folate) deficiency?

in Question 16 upvotes 6 years ago

The conversation is about hair loss and correcting vitamin deficiencies, specifically D3, B12, and folic acid. The user is considering if these deficiencies impact hair growth and mentions starting supplements.

community B5 (Pantothenic acid), B7 (Biotin), B12

in Treatment 4 upvotes 2 years ago

The conversation discusses the effects of B5 (Pantothenic acid), B7 (Biotin), and B12 on hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Stem Cells May Get Rid Of Balding FOREVER!

in Technology 11 upvotes 1 year ago

Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

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