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    Glossary DNA Methyltransferase 1

    maintains DNA methylation patterns during cell division

    DNA Methyltransferase 1 (DNMT1) is an enzyme that plays a crucial role in maintaining DNA methylation patterns during cell division. It adds methyl groups to the cytosine bases of DNA, which can regulate gene expression by turning genes on or off. This process is essential for normal development, genomic stability, and cellular differentiation.

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    1. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012 · 72 citations
    2. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012 · 1 citations
    3. 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis Journal of Investigative Dermatology · 2018
    4. Epigenetic Modulation of ESR1 and DNMT3A Following Finasteride Exposure: Implications for Female Reproductive Function Physiology · 2026
    5. OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases Stem Cell Research & Therapy · 2019 · 57 citations
    6. DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018 · 1 citations
    7. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    8. Hypothalamic DNA methylation in rats with dihydrotestosterone‐induced polycystic ovary syndrome: effects of low‐frequency electro‐acupuncture Experimental physiology · 2018 · 18 citations
    9. Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice Journal of Tissue Engineering and Regenerative Medicine · 2022 · 6 citations
    10. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
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