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GlossaryDNA Methyltransferase 1

maintains DNA methylation patterns during cell division

DNA Methyltransferase 1 (DNMT1) is an enzyme that plays a crucial role in maintaining DNA methylation patterns during cell division. It adds methyl groups to the cytosine bases of DNA, which can regulate gene expression by turning genes on or off. This process is essential for normal development, genomic stability, and cellular differentiation.

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Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

72 citations, July 2012 in “Journal of Investigative Dermatology”

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

1 citations, September 2012 in “Journal of Investigative Dermatology”

Aging reduces stem cell activation, leading to hair loss in mice lacking a specific enzyme.

research DNA Methylation as an Epigenetic Memory Keeper During Skin Development and Regeneration

1 citations, January 2018 in “Stem cell biology and regenerative medicine”

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

research Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling

28 citations, August 2018 in “BMC genomics”

DNA methylation changes are linked to hair growth cycles in goats.

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

research Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

24 citations, April 2020 in “Cells”

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

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community DNA Trichotest reliable? & topical spironolactone for Cis males

in Research/Science 1 upvotes 2 months ago

The DNA Trichotest is considered unreliable for predicting hair loss treatment responses, and topical spironolactone is questioned for its effectiveness and safety in cis males. Finasteride and Dutasteride are recommended as more reliable treatments for androgenic alopecia.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 9 months ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community Topical Melatonin for mild aga

in Chat 2 upvotes 9 months ago

The conversation is about an 18-year-old male considering topical finasteride for hair loss and asking about the effectiveness of topical melatonin for hair regrowth and density. No specific treatments were confirmed to be used.

community Trichotest results in… min not on my list! Just Fin/Dut, Zinc… and the insanely expensive latanoprost & prostaquinon.

in Technology 22 upvotes 2 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Bryan Johnson used a customized formula by Roots byGA to restore his hair

in Treatment 23 upvotes 1 month ago

Bryan Johnson used a customized hair restoration formula from Roots byGA, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. Many users are skeptical of the effectiveness and uniqueness of the treatment, suggesting that standard treatments like Minoxidil and Dutasteride are more reliable.

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