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    GlossaryDNA Methyltransferase 1

    maintains DNA methylation patterns during cell division

    DNA Methyltransferase 1 (DNMT1) is an enzyme that plays a crucial role in maintaining DNA methylation patterns during cell division. It adds methyl groups to the cytosine bases of DNA, which can regulate gene expression by turning genes on or off. This process is essential for normal development, genomic stability, and cellular differentiation.

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      community DNA Trichotest reliable? & topical spironolactone for Cis males

      in Research/Science  1 upvotes 2 months ago
      The DNA Trichotest is considered unreliable for predicting hair loss treatment responses, and topical spironolactone is questioned for its effectiveness and safety in cis males. Finasteride and Dutasteride are recommended as more reliable treatments for androgenic alopecia.

      community DNA Testing by Roots by Genetic Arts

      in Research/Science  3 upvotes 9 months ago
      A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

      community Topical Melatonin for mild aga

      in Chat  2 upvotes 9 months ago
      The conversation is about an 18-year-old male considering topical finasteride for hair loss and asking about the effectiveness of topical melatonin for hair regrowth and density. No specific treatments were confirmed to be used.

      community Bryan Johnson used a customized formula by Roots byGA to restore his hair

      in Treatment  23 upvotes 1 month ago
      Bryan Johnson used a customized hair restoration formula from Roots byGA, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. Many users are skeptical of the effectiveness and uniqueness of the treatment, suggesting that standard treatments like Minoxidil and Dutasteride are more reliable.

      community Average tressless user after taking oral minoxidil

      in Satire  1439 upvotes 1 year ago
      The conversation is about hair loss and the use of minoxidil (Minoxidil) and finasteride (Fin) as treatments. The conclusion is that some users have seen success in maintaining their hair with minoxidil, but there are varying opinions on the effectiveness of the treatments.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community I got an idea to cure baldness but i need your help

      in Satire  94 upvotes 1 year ago
      User suggests finding unknown baldness cure by applying random items on scalp and reporting results after 6 months. Various users humorously agree to try different substances, including whale sperm and hydrochloric acid.

      community Genetic testing to determine individualized hairloss treatment?

      in Research/Science  10 upvotes 1 year ago
      A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

      community Any luck with peppermint oil?

      in Question  6 upvotes 6 years ago
      A user stopped using minoxidil due to scalp irritation and is now using peppermint oil, noticing improved hair appearance but no growth yet. They are seeking a minoxidil brand that doesn't irritate the scalp and asking if others have had success with peppermint oil for hair loss.

      community 3 and a half month progress pic

      in Progress Pictures  259 upvotes 1 month ago
      The user shared a 3.5-month hair regrowth update using finasteride, 5% topical minoxidil, micro-needling, and keto shampoo, along with lifestyle changes like reducing stress and improving diet. They encourage others to stay committed to their regimen despite initial slow progress.

      community Upcoming treatment ideas in the future

      in Research/Science  10 upvotes 1 month ago
      Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.

      community Androgen degraders for hair loss

      in Research/Science  62 upvotes 3 months ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 3 months ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

      community Fagron TrichoTest says Finasteride won't help

      in Treatment  11 upvotes 5 months ago
      The user received a Fagron TrichoTest indicating that Finasteride, Dutasteride, and Minoxidil are not effective for them, recommending Latanoprost, Spironolactone, IGrantine-F1 TM, and Trichoxidil instead. Other users expressed skepticism about the test's validity and suggested sticking with proven treatments like Finasteride and Dutasteride.

      community Wait, this is actually working?! Feb - Jun

      in Is this regrowth?  116 upvotes 5 months ago
      The user experienced hair regrowth after 4 months of using topical finasteride and minoxidil, 2 weeks of dermatolling, and possibly tretinoin. They also noted improved mental health and reduced weight training.

      community Stress make you more androgen sensitive

      in Chat  19 upvotes 6 months ago
      Stress can increase androgen sensitivity, potentially worsening hair loss. Treatments discussed include Minoxidil, finasteride, and RU58841.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 7 months ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

      community Wish me luck,i hope these will help ne regrow my hair

      in Minoxidil  8 upvotes 8 months ago
      A user hopes to regrow hair using a routine of Min/fin solution twice daily, dermarolling twice weekly, multivitamins daily, and biotin twice daily. Another user doubts the effectiveness of biotin and multivitamins.

      community Sucess story for you guys, pics are 10+ years apart.

      in Progress Pictures  311 upvotes 9 months ago
      A user shared a success story showing hair regrowth over 10 years, attributing it to quitting creatine and taking 0.5mg finasteride. Some commenters were skeptical about creatine's impact, while others inquired about side effects, and the original poster reported no negative effects from finasteride.