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    GlossaryGenetic Mutations

    changes in DNA sequence that can affect traits or health

    Genetic mutations are changes in the DNA sequence of an organism's genome. These alterations can occur naturally during DNA replication or be induced by environmental factors such as radiation or chemicals. While some mutations are harmless or even beneficial, others can lead to diseases or disorders, including various forms of alopecia.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  138 upvotes 3 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community Diffuse thinning is the worst man

      in Chat  248 upvotes 11 months ago
      The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

      community One and a half year on meds (fin/dut, minox)

      in Progress Pictures  54 upvotes 2 months ago
      The user has been using oral minoxidil, finasteride, and dutasteride to prevent hair loss, despite not showing significant balding. Many commenters believe the treatment is excessive, while some support early prevention.