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GlossaryGenotoxicity

ability of substances to damage cellular genetic information

Genotoxicity refers to the ability of certain substances to damage the genetic information within a cell, causing mutations that may lead to cancer. This term is important in both medical and environmental contexts, as it helps assess the potential risks of chemicals, drugs, and other agents to human health and the environment.

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research Validation of Replacement of the Synthetic Food Dye 'Sunset Yellow'-Induced Hepatotoxicity and Genotoxicity with the Nutraceutical 'Curcumin' in Mice

8 citations , January 2016

Curcumin can safely replace Sunset Yellow as a food colorant.

research Genotoxicity of Rice Bran Oil Extracted by Supercritical CO2 Extraction

7 citations , January 2014 in “Biological & pharmaceutical bulletin”

Rice bran oil extracted by supercritical CO2 is considered non-genotoxic.

research Cytotoxicity And Genotoxicity Of Tridax Procumbens L. In Allium Cepa

4 citations , November 2015 in “Research Journal of Medicinal Plant”

Tridax procumbens extracts can harm cell division and increase cell death in onion roots.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations , June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

38 citations , September 2017 in “Cancer Research”

Boosting certain cell signals can prevent hair loss from cancer treatments.

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