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GlossaryGenotoxicity

ability of substances to damage cellular genetic information

Genotoxicity refers to the ability of certain substances to damage the genetic information within a cell, causing mutations that may lead to cancer. This term is important in both medical and environmental contexts, as it helps assess the potential risks of chemicals, drugs, and other agents to human health and the environment.

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research Validation of Replacement of the Synthetic Food Dye 'Sunset Yellow'-Induced Hepatotoxicity and Genotoxicity with the Nutraceutical 'Curcumin' in Mice

8 citations, January 2016

Curcumin can safely replace Sunset Yellow as a food colorant.

research Genotoxicity of Rice Bran Oil Extracted by Supercritical CO2 Extraction

7 citations, January 2014 in “Biological & pharmaceutical bulletin”

Rice bran oil extracted by supercritical CO2 is considered non-genotoxic.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Applications and Risks of Nanomaterials Used in Regenerative Medicine, Delivery Systems, Theranostics, and Therapy

28 citations, January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems”

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

research Scientific Opinion on the Safety of Coriander Seed Oil as a Novel Food Ingredient

18 citations, October 2013 in “EFSA Journal”

Coriander seed oil is safe for healthy adults at up to 600 mg per day.

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