TLDR Finasteride may help treat childhood brain tumors by activating certain genes.
The study presented at the ASPET 2023 Annual Meeting investigated the epigenetic effects of finasteride on medulloblastoma, a common childhood brain tumor. Finasteride, a 5-alpha reductase inhibitor, was found to modulate the methylation of the BTG2 and CD244 genes, leading to their upregulation. BTG2 acts as an inhibitor of medulloblastoma cell proliferation and differentiation, while CD244 enhances natural killer cell activity against the tumor. The findings suggest that finasteride-induced upregulation of these genes could be explored as a potential therapeutic approach for medulloblastoma.
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July 2006 in “Dermatologic therapy” The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
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October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces hair growth and is safe for women with excessive hair.
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October 1992 in “Hormone and Metabolic Research” Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
June 2025 in “Pharmaceuticals” Finasteride use may increase suicidality risk, especially in young men.
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
