TLDR Histone modification is key in treating chronic inflammatory skin diseases.
Histone modification is crucial in the pathogenesis and treatment of chronic inflammatory skin diseases such as psoriasis, atopic dermatitis, lupus, systemic sclerosis, contact dermatitis, lichen planus, and alopecia areata. This review highlights the role of histone modification as an epigenetic regulatory approach, offering insights into managing these disorders. Therapeutic interventions targeting histone modifications show promise in effectively managing these conditions. The review also explores current and potential therapeutic strategies and emphasizes the future research prospects in this area, aiming for innovative treatments and better patient outcomes.
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