Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation

    February 2019 in “ Journal of Cutaneous Pathology ”
    Danielle Leavitt, Michael Wells, Phammela Abarzua … Christine G. Lian
    Studysummary This study suggests that the epigenetic marker 5-hmC may dynamically influence hair follicle bulge activation during anagen growth in mice, warranting further investigation into its role in stem cell regulation.
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    Research cited in this study 8

    1. Topical Valproic Acid Increases Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis Journal of Dermatology · 2014
    2. A Prostaglandin D-Synthase-Positive Mast Cell Gradient Characterizes Scalp Patterning Journal of Cutaneous Pathology · 2013
    3. Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model Journal of Dermatological Science · 2013
    4. Dissecting the Bulge in Hair Regeneration Journal of Clinical Investigation · 2012
    5. Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells Cell stem cell · 2011
    6. The Hair Growth Promoting Effect of Ascorbic Acid 2-Phosphate, a Long-Acting Vitamin C Derivative Journal of Dermatological Science · 2006
    7. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    8. Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture Archives of Dermatological Research · 2005

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    2. Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    3. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    4. Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles In vitro cellular & developmental biology. Animal · 2008
    5. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003