Dynamics and Epigenetics of the Epidermal Differentiation Complex

February 2024 in “ Epigenomes ”

Wiesława Leśniak

epidermal differentiation complex EDC DNA methylation histone modifications chromatin architecture topologically associating domains TADs epidermal differentiation skin homeostasis

TLDR Epigenetic mechanisms control skin development by regulating gene expression.

The document "Dynamics and Epigenetics of the Epidermal Differentiation Complex" explores the regulation of the Epidermal Differentiation Complex (EDC), crucial for skin development. It highlights the role of epigenetic mechanisms, such as DNA methylation and histone modifications, in controlling EDC gene expression. The study emphasizes the importance of chromatin architecture and topologically associating domains (TADs) in facilitating coordinated gene expression necessary for epidermal differentiation. The findings underscore the dynamic interplay between genetic and epigenetic factors in maintaining skin homeostasis and responding to environmental stimuli.

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Research cited in this study

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Dynamics and Epigenetics of the Epidermal Differentiation Complex

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