Rosmarinus Officinalis and Skin: Antioxidant Activity and Possible Therapeutic Role in Cutaneous Diseases

The document "Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases" discusses the potential therapeutic benefits of rosemary (Rosmarinus officinalis) in treating various skin conditions. The plant's bioactive compounds, including rosmarinic acid, carnosic acid, carnosol, and rosemary essential oil, have been studied for their antioxidant, anti-inflammatory, and anti-cancer properties. The plant has shown potential in treating UV-induced photoaging, atopic dermatitis, and pollution-induced skin aging. Rosemary's bioactive compounds have been found to inhibit protein glycation and oxidative stress, key factors in skin aging, and to downregulate inflammation-associated genes. The document also discusses the potential of rosemary in treating androgenetic alopecia, comparing its effectiveness to Minoxidil 2%. However, more research is needed to fully understand the molecular mechanisms involved and to develop effective therapeutic delivery systems.