Systemic Immunotherapies

    May 2023 in “ Elsevier eBooks
    Sarah Benton, Ronda S. Farah, Maria Hordinsky
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    TLDR Systemic immunotherapies are used for immune-related hair loss but not usually for genetic hair loss, unless the patient has both conditions.
    Systemic immunotherapies, including oral steroids, janus kinase (JAK) inhibitors, methotrexate, cyclosporine, and biologics, are often used to treat immune-mediated hair loss conditions like alopecia areata and cicatricial alopecias. These treatments are not typically used for androgenetic alopecia (AGA), but some existing AGA treatments, such as antihistamines, photobiomodulation, and platelet-rich plasma, do have anti-inflammatory effects. Systemic immunotherapy may be indicated for AGA patients if they also have immune-mediated hair loss like alopecia areata.
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