Understanding Causes of Hair Loss in Women

    May 2021 in “ Dermatologic Clinics ”
    Neil S. Sadick, Suleima Arruda
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    TLDR The conclusion is that hair loss in women is caused by a mix of hormonal, environmental, and genetic factors, and treatments should target these various causes.
    Female pattern hair loss (FPHL) is a condition affecting around 20% of adult women in the U.S., with a higher prevalence in White women and often starting post-menopause. The causes of FPHL are complex, involving hormonal, environmental, and genetic factors that lead to microinflammation and oxidative stress. Androgens, stress hormones like cortisol, UV radiation, pollutants, and lifestyle choices all contribute to the condition. Treatments should focus on the multifaceted nature of hair loss, targeting inflammation, oxidative stress, and hormonal imbalances. New therapies such as platelet-rich plasma, low-level laser therapy, and nutraceuticals are promising as they address multiple aspects of hair loss and aim to improve the immune response. The document suggests a shift in treatment strategies to encompass the broader pathophysiology of hair loss.
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