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    Baseline Neutrophil-To-Lymphocyte Ratio Stratifies Early Trichoscopic Response To Platelet-Rich Plasma-Based Regimens In Non-Scarring Alopecia: A Real-World Cohort With Internal Validation Using An Interpretable Neural Network

    April 2026 in “ Life ”
    Adelina Vrapcea, Sarmis-Marian Săndulescu, Eleonora Daniela Ciupeanu-Călugăru … Cătălina Gabriela Pisoschi
    Studysummary In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.
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    Research cited in this study 32

    1. Systemic Inflammation Marker Alterations in Severe Alopecia Areata Patients Treated with Janus Kinase Inhibitors Journal of Clinical Medicine · 2026
    2. Platelet-Rich Plasma in the Management of Alopecia: A Systematic Review and Meta-Analysis of Clinical Evidence Dermatology and Therapy · 2025
    3. Comparison of Current International Guidelines for the Management of Alopecia Areata: Comprehensive Review International Journal of Molecular Sciences · 2025
    4. Comparison of the Efficacy of Platelet-Rich Plasma With Topical Minoxidil in Treating Patients With Androgenetic Alopecia: A Systematic Review of Clinical Trials Skin Health and Disease · 2025
    5. Platelet-Derived Extracellular Vesicles Promote Hair Follicle Growth Through Beta-Catenin Signaling Pathway Platelets · 2025
    6. Inflammatory Signatures and Biological Markers in Platelet-Rich Plasma Therapy for Hair Regrowth: A Comprehensive Narrative Analysis Diagnostics · 2025
    7. Platelet-Rich Plasma-Derived Exosomes Stimulate Hair Follicle Growth Through Activation of the Wnt/β-Catenin Signaling Pathway Regenerative Therapy · 2025
    8. A Prospective Study of Exosome Therapy for Androgenetic Alopecia Aesthetic Plastic Surgery · 2025
    9. A Pilot Randomized Controlled Trial Evaluating the Efficacy of an Exosome-Containing Plant Extract Formulation for Treating Male Alopecia Life · 2025
    10. Hematological Ratios as an Indicator of Severity in Alopecia Areata: A Retrospective Nationwide Study PLoS ONE · 2024
    11. Complete Blood Collection-Based Systemic Inflammation Biomarkers as a Severity Biomarker in Alopecia Areata: A Cross-Sectional Study Acta Dermato Venereologica · 2024
    12. Evaluation of Serum Inflammatory Markers and Their Relationship to Treatment Response in Alopecia Areata Patients Dermatology Practical & Conceptual · 2024
    13. Recommendations on the Clinical Management of Androgenetic Alopecia: A Consensus Document from the Spanish Group of Trichology of the Spanish Academy of Dermatology and Venereology Actas Dermo-Sifiliográficas · 2024
    14. European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    15. Alopecia Areata: What's New in the Epidemiology, Comorbidities, and Pathogenesis? Journal of Dermatological Science · 2023
    16. The Dermatoscope in the Hair Clinic: Trichoscopy of Scarring and Nonscarring Alopecia Journal of the American Academy of Dermatology · 2023
    17. Androgenetic Alopecia: An Update JAAD International · 2023
    18. Androgenetic Alopecia: Therapy Update Drugs · 2023
    19. Telogen Effluvium, Diagnosis and Management: A Narrative Review International Journal of Biomedicine · 2023
    20. A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia Aesthetic Plastic Surgery · 2022
    21. The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study Aesthetic Surgery Journal · 2021
    22. Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial Journal of The American Academy of Dermatology · 2020
    23. Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study Acta dermato-venereologica · 2020
    24. As a Carrier–Transporter for Hair Follicle Reconstitution, Platelet-Rich Plasma Promotes Proliferation and Induction of Mouse Dermal Papilla Cells Scientific Reports · 2017
    25. Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017
    26. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    27. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    28. Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia Asian Journal of Transfusion Science · 2015
    29. Androgenetic Alopecia and Microinflammation International Journal of Dermatology · 2000
    30. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    31. Cytokines and Growth Factors Influence Hair Growth In Vitro: Possible Implications for the Pathogenesis and Treatment of Alopecia Areata Archives of Dermatological Research · 1996
    32. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993