Role of Skin Microbiome and Exosomes in Hair Regeneration and Disorders in Diseases Like Alopecia and Acne: A Comprehensive Review

    February 2026 in “ International Journal of Web of Multidisciplinary Studies ”
    ASHWIN GS, Balamurugan Appakalai N, Dr HIRTHIK ROSHAN, Dr KARMUGILAN S, Dr VENUVAIDESH CHENGA REDDY, PARTHASARATHY S
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    This comprehensive review examines the role of the skin microbiome and exosomes in hair disorders like alopecia, acne, and seborrheic dermatitis. It highlights the impact of microbial dysbiosis on hair follicle health, leading to inflammation and hair loss, and suggests that restoring microbial balance could be therapeutic. Exosomes, acting as molecular couriers, carry growth factors that promote hair follicle regeneration and immune balance. The review emphasizes the potential of microbiome restoration strategies and exosome-based therapies in developing precision scalp medicine and novel regenerative interventions for common hair disorders. Understanding the interaction between the microbiome and exosomes is crucial for advancing treatments.
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