Androgenetic Alopecia: Update on Etiology

    March 2021 in “ Dermatological reviews ”
    Rachita Dhurat, Sanober Burzin Daruwalla
    Studysummary This review discusses recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia in males, females, and children, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 47

    1. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    2. The Diagnosis of Androgenetic Alopecia in Children: Considerations of Pathophysiological Plausibility Australasian Journal of Dermatology · 2019
    3. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    4. Genetic and Molecular Aspects of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    5. NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in Various Pelage Hair Follicle Types ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2017
    6. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2017
    7. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    8. Apoptosis in Follicles of Individuals with Female Pattern Hair Loss Is Associated with Perifollicular Microinflammation International Journal of Cosmetic Science · 2016
    9. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    10. Female Pattern Hair Loss: A Clinical and Pathophysiological Review Anais Brasileiros De Dermatologia · 2015
    11. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    12. Similar Response Patterns to Topical Minoxidil Foam 5% in Frontal and Vertex Scalp of Men with Androgenetic Alopecia: A Microarray Analysis British Journal of Dermatology · 2014
    13. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    14. Evidence for a Polygenic Contribution to Androgenetic Alopecia British Journal of Dermatology · 2013
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    17. Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology Journal of Investigative Dermatology · 2013
    18. Evaluation of Perifollicular Inflammation of Donor Area During Hair Transplantation in Androgenetic Alopecia and Its Comparison With Controls International Journal of Trichology · 2013
    19. Factors Associated With Female Pattern Hair Loss And Its Prevalence In Taiwanese Women: A Community-Based Survey Journal of The American Academy of Dermatology · 2012
    20. Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments Dermatologic Clinics · 2012
    21. Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration Journal of Investigative Dermatology · 2012
    22. Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth International Journal of Trichology · 2012
    23. Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases PLOS Genetics · 2012
    24. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    25. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    26. Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia British Journal of Dermatology · 2012
    27. Association Analysis of Estrogen Receptor Beta Gene (ESR2) Polymorphisms with Female Pattern Hair Loss British Journal of Dermatology · 2011
    28. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011
    29. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    30. Male Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2010
    31. Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey British Journal of Dermatology · 2010
    32. Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss British Journal of Dermatology · 2009
    33. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    34. Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008
    35. Different Patterns of 5α-Reductase Expression, Cellular Distribution, and Testosterone Metabolism in Human Follicular Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2008
    36. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    37. Androgenetic Alopecia in Children: Report of 20 Cases British Journal of Dermatology · 2005
    38. Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis Journal of Dermatological Science · 2004
    39. Is Androgenetic Alopecia a Photoaggravated Dermatosis? Dermatology · 2003
    40. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    41. Female Pattern Hair Loss Clinical and Experimental Dermatology · 2002
    42. Effects of Minoxidil 2% vs. Cyproterone Acetate Treatment on Female Androgenetic Alopecia: A Controlled, 12-Month Randomized Trial British Journal of Dermatology · 2002
    43. Treatment of Hair Loss The New England Journal of Medicine · 1999
    44. Diffuse Female Hair Loss: Are Androgens Necessary? British Journal of Dermatology · 1999
    45. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998
    46. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
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    Related research 6

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    6. Hair Loss: An Overview PubMed · 2001