Hair Follicles and Their Role in Skin Health

    December 2006 in “ Expert Review of Dermatology ”
    Man Yu, Andreas M. Finner, Jerry Shapiro … Kevin J. McElwee
    Studysummary This review discusses the multifaceted roles of hair follicles in skin health, including potential contributions to skin neoplasias, and reports no new results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on tandfonline.com →
    Discuss this study in the Community →

    Research cited in this study 54

    1. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006
    2. Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia Current pharmaceutical design · 2006
    3. Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells Stem Cells and Development · 2006
    4. Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride Skin Pharmacology and Physiology · 2006
    5. Gene Expression Profiling Gets to the Root of Human Hair Follicle Stem Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    6. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    7. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005
    8. Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling Proceedings of the National Academy of Sciences of the United States of America · 2005
    9. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005
    10. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    11. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    12. Hair Follicle-Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Cancer Research · 2005
    13. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    14. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    15. Detection of Human Papillomavirus Type 56 DNA in Hair Follicles in the Genital Area of a Woman No Longer Suffering from Viral Warts British Journal of Dermatology · 2004
    16. Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo Journal of Investigative Dermatology · 2004
    17. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    18. Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra) Plastic and Reconstructive Surgery · 2004
    19. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    20. Molecular Biology of Hair Morphogenesis: Development and Cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003
    21. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003
    22. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    23. Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes American Journal of Physiology-cell Physiology · 2003
    24. Molecular Genetic and Endocrine Mechanisms of Hair Growth Hormone Research in Paediatrics · 2003
    25. Cyclic Alopecia in Msx2 Mutants: Defects in Hair Cycling and Hair Shaft Differentiation Development · 2002
    26. Clinical and Molecular Diagnostic Criteria of Congenital Atrichia with Papular Lesions Journal of Investigative Dermatology · 2002
    27. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    28. Histologic Study of the Regeneration Process of Human Hair Follicles Grafted onto SCID Mice after Bulb Amputation Journal of Investigative Dermatology Symposium Proceedings · 2001
    29. Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    30. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    31. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    32. Hepatocyte Growth Factor Activator Expressed in Hair Follicles Is Involved in In Vitro HGF-Dependent Hair Follicle Elongation Journal of Dermatological Science · 2001
    33. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    34. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    35. Induction of Basal Cell Carcinomas and Trichoepitheliomas in Mice Overexpressing GLI-1 Proceedings of the National Academy of Sciences · 2000
    36. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    37. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    38. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    39. What Controls Hair Follicle Cycling? Experimental dermatology · 1999
    40. Cytokeratin 15 Expression in Trichoepitheliomas and a Subset of Basal Cell Carcinomas Suggests They Originate from Hair Follicle Stem Cells Journal of Cutaneous Pathology · 1999
    41. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    42. Expression of Vascular Endothelial Growth Factor (VEGF) in Various Compartments of the Human Hair Follicle Archives of Dermatological Research · 1998
    43. Splitting Hairs: Molecular Mechanisms of Hair and Feather Development Cell · 1998
    44. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    45. Hair Regrowth Dermatologic Clinics · 1998
    46. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    47. Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse Journal of Investigative Dermatology · 1996
    48. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    49. Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis Developmental dynamics · 1994
    50. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993
    51. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988
    52. Topical Minoxidil (3%) in Extensive Alopecia Areata, Including Long-Term Efficacy Journal of The American Academy of Dermatology · 1987
    53. Role of Macrophages in Collagen Resorption During Hair Growth Cycle Journal of Ultrastructure Research · 1969
    54. Growth of the Hair Physiological Reviews · 1954

    Related research 5

    1. Hair Loss and Hirsutism Management 2019
    2. Treatments of Hereditary Hair Loss (Alopecia) 2018
    3. Electron Paramagnetic Resonance Spectroscopy for Investigating Murine Telogen Skin After Spontaneous or Depilation-Induced Hair Growth Journal of Dermatological Science · 2008
    4. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    5. Hair Root Characteristics of the Human Scalp Hair in Health and Disease RePub (Erasmus University, Rotterdam) · 1982