Stress-Induced Premature Senescence of Dermal Papilla Cells Compromises Hair Follicle Epithelial-Mesenchymal Interaction
January 2017
in “
Journal of Dermatological Science
”
dermal papilla cells hair follicle aging H2O2 oxidative stress apoptosis gene expression protein secretion dermal fibroblasts epidermal differentiation follicular differentiation hair follicle stem cell growth inflammatory cytokines IL-6 clonal keratinocyte growth telogen anagen epithelial-mesenchymal interaction hydrogen peroxide interleukin-6
Studysummary This study suggests that stress-induced premature senescence of dermal papilla cells may contribute to hair follicle aging by impairing critical epithelial-mesenchymal interactions and promoting inflammatory cytokine production.
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