Quantitative Study of the Human Hair Follicle in Normal Scalp and Androgenetic Alopecia

August 1993 in “ Journal of Cutaneous Pathology ”

M. V. Alcaraz, Alberto J. Villena, I. Perez de Vargas

hair follicle androgenetic alopecia miniaturized follicles dermal papilla cell nuclei hair loss male pattern baldness

TLDR Alopecia causes smaller hair follicles and affects growth-related structures.

This scientific paper presents a quantitative study of the human hair follicle in normal scalp and androgenetic alopecia. The study found that individuals with androgenetic alopecia had smaller hair follicles and a higher percentage of miniaturized follicles compared to those with normal scalp. The study also found that the dermal papilla, a structure important for hair growth, is smaller in volume and has fewer cell nuclei in androgenetic alopecia compared to normal scalp. The size of the papilla cell nuclei also increases as alopecia develops, indicating its significant role in hair loss and growth. The study highlights the need for more quantitative studies on the hair follicle in normal scalp and androgenetic alopecia to better understand the hair follicle.

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