Evaluation of Derma Genie-H001 as a Functional Cosmetic Ingredient for Hair Loss Improvement: Assessing Anti-Inflammatory, Antioxidative, Photoprotective, Antiandrogenic, and Hair Growth-Inductive Effects

March 2024 in “ Asian journal of beauty & cosmetology ”

S.H. Park, Nayeon Han, Bo Liu, Yuna Choi, Seunghee Bae, Sungkwan An, Jung Min Lee

Derma Genie™-H001 anti-inflammatory antioxidative photoprotective antiandrogenic hair growth-inductive human dermal papilla cells HDPCs hydrogen peroxide UVB-induced cytotoxicity hair growth-related genes hair loss-related genes Derma Genie UVB

TLDR Derma Genie™-H001 can help prevent hair loss and promote hair growth.

The study evaluated Derma Genie™-H001, a blend of five medicinal plants, for its potential as a functional cosmetic ingredient to improve hair loss. The research demonstrated that Derma Genie™-H001 has significant anti-inflammatory, antioxidative, photoprotective, and antiandrogenic properties. It effectively reduced inflammatory mediators and protected human dermal papilla cells (HDPCs) from hydrogen peroxide and UVB-induced cytotoxicity. Additionally, it increased the expression of hair growth-related genes and decreased the expression of hair loss-related genes in HDPCs. These findings suggest that Derma Genie™-H001 could be a valuable natural ingredient for hair loss prevention and hair growth promotion.

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