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research Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner

17 citations , December 2001 in “Journal of Investigative Dermatology”

This study found that osteopontin mRNA is abundantly expressed in dermal papilla cells during the catagen phase of hair growth in rats, suggesting a role in this phase.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , July 2004 in “Journal of Dermatological Science”

In this study, decreased expression of BMP2 and ephrin A3 and increased NT-4 gene expression were observed in dermal papilla cells from androgenic alopecia-affected skin, suggesting potential roles in hair growth regulation.

research Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats

7 citations , July 2024 in “Animals”

In this study, the researchers observed that higher expression of the Sonic hedgehog gene in cashmere goats' hair follicle cycles is associated with increased cell proliferation and reduced apoptosis, suggesting its role in enhancing cashmere quality.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.

research Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression

6 citations , March 2019 in “Dermatologic surgery”

This study found that storing hair follicle grafts in chilled ATPv-supplemented saline was most effective for preserving trichogenic gene expression, compared to other storage solutions and temperatures.

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Community Join

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community finastreid + min and derma stamp 1x /week . is it a progress?

in Is this regrowth? 36 upvotes 2 months ago

The user started oral finasteride in October 2025, switched to topical finasteride and minoxidil in mid-2026, and uses a dermastamp weekly. They are unsure about regrowth progress and feel insecure about their hairline.

community 2 months on topical minoxidil and derma rolling

in Transgender 10 upvotes 9 months ago

A 19-year-old trans female has been using topical minoxidil and dermarolling for nearly two months, alongside oral minoxidil, finasteride, spironolactone, and estrogen. She noticed significant hair improvement after starting topical minoxidil and dermarolling.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community Help me prepare with advise to get Dutasteride with my doc and dermatologist

17 upvotes 1 month ago

The user has been using finasteride, minoxidil, and derma stamping for hair loss but is considering switching to dutasteride due to lack of improvement. They are seeking advice on obtaining dutasteride, which is off-label in Denmark, and are considering ordering it online if not prescribed.

community (Serious) News and discussion on potential treatments

28 upvotes 1 year ago

Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

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Learn

3 / 10 results

learn GHK-Cu

Copper peptide used in skin and hair cosmetics

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Valproic acid

Anti-seizure and mood-stabilising drug

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Clinics

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Experts

5 / 5 results