March 2024 in “Advanced healthcare materials/Advanced Healthcare Materials” This study found that generating pluripotent stem cell-derived skin organoids in a 3D bioprinted hydrogel device improved keratinocyte differentiation and hair follicle formation while reducing necrosis.
25 citations
,
February 2024 in “Biomaterials” In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.
January 2024 in “Annals of Dermatology” This study highlights the lack of sufficient Korean epidemiological research examining the psychosocial aspects of female pattern hair loss, the leading cause of hair loss among women.
November 2023 in “Computational and Structural Biotechnology Journal” This study reports the development of a prototype robotic hair transplant system capable of efficiently harvesting and implanting hair grafts, showing promising accuracy and performance in tests using a spherical scalp phantom.
November 2023 in “Plastic and Reconstructive Surgery – Global Open” This survey reported that Americans often view hair loss as affecting their attractiveness and consider hair transplantation a valuable option, with women willing to pay more than men despite being less likely to undergo the procedure.
October 2023 in “Journal of cosmetic dermatology” This study found that among over 10,000 hair transplantation patients, only four cases of scalp necrosis occurred, highlighting that timely diagnosis and treatment can prevent serious complications and improve outcomes, with most cases resolving within 2–3 weeks.
October 2023 in “Facial Plastic Surgery” This article discusses non-scalp donor hair harvesting for advanced hair loss and scarring camouflage but reports no new clinical results, emphasizing the technical challenges and expertise required in follicular unit excision.
August 2023 in “Tzu Chi Medical Journal” This study at a medical center in Eastern Taiwan found that female alopecia has diverse causes, including nutrient deficiencies, autoimmune diseases, psychological stress, thyroid conditions, and COVID-19 vaccination, with iron deficiency affecting 70.3% of cases.
7 citations
,
August 2023 in “Dermatologic Surgery” In this study, researchers reported that a new skin-responsive FU excision device consistently succeeded in all patients of African descent, showing a mean graft transection rate of less than 10%, with skin thickness and firmness identified as major factors affecting graft attrition rate.
July 2023 in “Dermatology practical & conceptual” This study found that women with Female Pattern Hair Loss had lower serum BDNF levels, which correlated with higher stress and depression, suggesting BDNF as a potential marker for psychological impacts in these patients.
1 citations
,
July 2023 in “Journal of the American Academy of Dermatology” This review reports that pressure-induced alopecias, occurring from ischemic pressure, are often reversible without treatment if diagnosed promptly, but prognosis varies with severity and treatment timing.
July 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study explains surgical techniques for hair transplantation using the sharp implanter method, emphasizing 11 key principles that optimize efficiency and precision, and reports high graft survival and natural hair density when these principles are followed.
3 citations
,
June 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the clinical spectrum and pathobiology of radiotherapy-induced alopecia and reports no new research findings, highlighting potential pathways for future targeted RIA management.
This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.
1 citations
,
May 2023 in “JAMA dermatology” Tight hairstyles can cause hair loss, which can be permanent if not treated early.
May 2023 in “Journal of Clinical Medicine” This review article reports recent advancements in understanding, diagnosing, and treating various hair loss conditions, like androgenetic alopecia and alopecia areata, including their genetic factors and new therapeutic options, while also examining the impact of COVID-19 on hair loss.
March 2023 in “Journal of Cosmetic Dermatology” This study found that hair transplant surgery significantly improved self-esteem and quality of life in patients with androgenetic alopecia.
8 citations
,
January 2023 in “Surgical Neurology International” This case report describes the successful use of percutaneous and endovascular embolization with PHIL embolic agent to treat a rare scalp arteriovenous fistula following a hair transplant.
7 citations
,
January 2023 in “Biofabrication” This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
1 citations
,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review examines current diagnosis and management strategies for hair loss in women with polycystic ovarian syndrome, reporting no new clinical findings and emphasizing the need for more targeted research in this area.
January 2023 in “Theranostics” This study demonstrated that a mechanical-chemical cascade involving dermal cell contraction and the activation of Piezo1 in epidermal cells is crucial for initiating interactions necessary for hair follicle regeneration in skin organoids.
January 2023 in “Skin appendage disorders” This study attempts to define normal post-transplant trichoscopic patterns in patients with androgenetic alopecia, highlighting several findings, but suggests longer follow-up studies are needed to confirm these observations.
45 citations
,
November 2022 in “Acta Biomaterialia” This study developed a biomimetic 3-D co-culture system that enhances the hair-inductive properties of human dermal papilla cell aggregates, potentially improving hair follicle tissue engineering.
October 2022 in “Journal of Cosmetic Dermatology” This study found that hair transplantation surgery significantly improved loneliness, anxiety, and depression in patients, with notable score reductions in these psychosocial outcomes post-surgery.
5 citations
,
August 2022 in “Psychology Research and Behavior Management” This study found that nearly half of those perceiving hair loss reported a significant impact on their quality of life, highlighting potential benefits of seeking medical advice for diagnosis and treatment.
1 citations
,
July 2022 in “Journal of Cosmetic Dermatology” This study reports that inflammatory complications, like lichen planopilaris, can occur after hair transplantation for androgenetic alopecia, despite being rare.
16 citations
,
June 2022 in “Acta biomaterialia” This study presents a bioprinter-based method for creating scalable, automated hair-inductive tissue grafts that showed improved hair shaft sprouting in mice by using suture guides to control orientation.
4 citations
,
June 2022 in “Clinical, cosmetic and investigational dermatology” In this study, researchers introduced the Sanusi FUE Score Scale to better predict and grade the difficulty of follicular unit excision hair transplantation by accounting for diverse hair and skin types, with further validation needed.
39 citations
,
March 2022 in “Nature Protocols” This study describes a protocol for generating hair-bearing skin organoids from human pluripotent stem cells, achieving full complexity resembling fetal skin tissue by day 130 in vitro.
15 citations
,
March 2022 in “Acta Biomaterialia” This study demonstrated that a 3D bioprinting technique using a gelatin/alginate hydrogel scaffold can regenerate entire hair follicles in mice, offering potential advancements in hair loss treatment.
16 citations
,
January 2022 in “International journal of molecular sciences” This review summarizes the influences of lifestyle factors such as smoking, alcohol, and diet on the pathogenesis of alopecia areata but reports no new clinical results.
11 citations
,
October 2021 in “Stem Cell Research & Therapy” This study reports that hair follicle-derived mesenchymal stem cells significantly reduced hair loss and inflammation in alopecia areata models, suggesting a potential therapeutic approach.
18 citations
,
October 2021 in “Journal of Advanced Research” This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.
5 citations
,
October 2021 in “Indian Journal of Plastic Surgery” This paper suggests that using semiconical blades and coronal slits in hair transplantation may reduce vascular damage compared to other techniques, potentially offering optimal slit creation.
3 citations
,
October 2021 in “Indian Journal of Plastic Surgery” This article identifies eight conditions that make patients unsuitable candidates for hair transplant surgery, emphasizing the importance of detailed consultations to recognize these factors, but reports no clinical results.
290 citations
,
August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
30 citations
,
April 2021 in “Journal of The American Academy of Dermatology” This review explains the evolution and current techniques of follicular unit transplantation for hair restoration, identifying conditions suitable for surgery and offering guidelines for dermatologists to assess candidate suitability, focusing on male and female pattern hair loss.
1 citations
,
February 2021 in “Journal of Dermatological Treatment” The researchers reviewed artificial hair implantation's history and controversies, noting that studies show promise but suffer from poor methodology. They emphasized the need for higher-quality research to confirm the procedure's safety and efficacy.
3 citations
,
January 2021 in “Skin appendage disorders” This review highlights the importance of recognizing neoplastic alopecia as a potential indicator of underlying metastatic neoplasia, as it may be mistaken for other scalp conditions like alopecia areata.
19 citations
,
October 2020 in “Journal der Deutschen Dermatologischen Gesellschaft” This review found that despite varied levels of stigmatization reported in studies, hair loss generally leads to stigmatization and a reduced quality of life, but specific research on this stigma is limited.
425 citations
,
June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
30 citations
,
April 2020 in “Stem Cell Research & Therapy” This study found that the PI3K-Akt signaling pathway is essential for regenerating new hair follicles when epidermal stem cells and skin-derived precursors are combined, suggesting potential therapeutic applications for hair regeneration.
22 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
16 citations
,
February 2020 in “The Laryngoscope” This study found that hair transplantation is feasible in patients with lichen planopilaris and frontal fibrosing alopecia, but outcomes are generally less favorable compared to other causes and these diseases may also develop after the procedure.
4 citations
,
January 2020 in “Journal of Cutaneous and Aesthetic Surgery” This case report highlights keloid formation as a rare complication at the donor site after follicular unit extraction hair transplantation, suggesting practitioners should be aware of procedure-associated risks.
14 citations
,
October 2019 in “Journal of Cellular Physiology” This study found that dermis micrografting improved hair growth and density in patients with androgenetic alopecia over 4, 6, and 12 months, suggesting it could be a novel treatment option.
September 2019 in “Journal of The American Academy of Dermatology” This research observed that during the 2 to 4 days following hair transplantation for androgenetic alopecia, patients may develop forehead and upper eyelid edema due to gravitational fluid movement and oozing of inflammatory fluid in the implanted area.
39 citations
,
May 2019 in “Journal of the American Academy of Dermatology” This study found that nonscarring alopecia in patients with systemic lupus erythematosus may indicate higher disease activity, as evidenced by specific histological and immunofluorescence changes.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.
219 citations
,
September 2016 in “American Journal of Psychiatry” This article reviews trichotillomania, highlighting its differences from OCD and recommending treatments like habit reversal therapy and specific medications, but reports no new clinical results.
41 citations
,
July 2015 in “Clinical and Experimental Dermatology” This review explores the connection between psoriasis and hair loss, noting that both the disease and its treatments can contribute to alopecia, and reports no new clinical results.
13 citations
,
June 2013 in “Actas Dermo-Sifiliográficas” This review details five cases of syphilitic alopecia, an uncommon symptom in syphilis affecting mainly men, emphasizing that dermatologists should be vigilant as it can appear as the sole symptom.
103 citations
,
December 2011 in “Journal of the American Academy of Dermatology” This review discusses current knowledge and management strategies for chemotherapy-induced alopecia, highlighting the need for better research prioritization and providing patient support materials, but reports no new clinical results.
75 citations
,
December 2011 in “British Journal of Dermatology” This review discusses female pattern hair loss, its psychological impact, and available treatments but provides no new clinical findings; the authors emphasize early intervention for better outcomes.
