TLDR Hair loss due to scalp metastasis from breast cancer, known as Neoplastic Alopecia, has a better survival rate than other scalp metastases and requires a biopsy for diagnosis.
The document reviewed 27 cases of Neoplastic Alopecia (NA), a rare condition where hair loss occurs due to scalp metastasis from primary tumors, predominantly breast cancer. It included a case report of an 85-year-old woman with a history of breast cancer who developed NA, diagnosed through clinical examination, dermoscopy, and histopathology. Dermoscopy was noted as beneficial for differential diagnosis, as NA lacks the classical criteria of other hair disorders. The latency period of NA varied, and its pathogenesis is believed to involve a scarring process from tumor cells. Scalp metastases generally suggest a poor prognosis, but NA-related cases have a relatively better outcome, with survival in years. Treatment options include radiotherapy, chemotherapy, and hormonal therapy, tailored to the cancer's characteristics and patient's health. Clinicians should consider NA when standard alopecia treatments fail, and a biopsy is essential for diagnosis. Recognizing NA is important as it may signal new or recurring metastatic cancer.
61 citations,
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January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
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March 2012 in “Journal of The American Academy of Dermatology” Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.
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January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
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3 citations,
January 2021 in “Skin appendage disorders” Hair loss due to scalp metastasis from breast cancer, known as Neoplastic Alopecia, has a better survival rate than other scalp metastases and requires a biopsy for diagnosis.
January 2021 in “Indian journal of dermatopathology and diagnostic dermatology” Trichoscopy is a reliable method for diagnosing hair and scalp disorders quickly and non-invasively.
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January 2019 in “Indian Journal of Dermatology” About 12% of children in Kota, Rajasthan, experience hair loss, mainly due to fungal infections, with early treatment advised to prevent worsening.
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March 2012 in “Journal of The American Academy of Dermatology” Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.
36 citations,
May 2011 in “Dermatologic therapy” No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
