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research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2

391 citations , September 2015 in “Journal of Clinical Lipidology”

This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.

research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

365 citations , March 2021 in “Frontiers in Bioengineering and Biotechnology”

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.

356 citations , December 1986 in “The journal of cell biology/The Journal of cell biology”

This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.

research Dual growth factor releasing multi-functional nanofibers for wound healing

355 citations , August 2013 in “Acta Biomaterialia”

This study found that a nanoparticle-in-nanofiber system significantly accelerated wound healing in rats by promoting angiogenesis and tissue regeneration more effectively than a commercial wound dressing.

research 40nm, but not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells after Transcutaneous Application on Human Skin

323 citations , April 2006 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that 40 nm nanoparticles can effectively penetrate into hair follicles and epidermal Langerhans cells in human skin samples, potentially enabling efficient transcutaneous vaccine delivery.

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community Any thoughts on DS Lab's Nanoxidil Serum?

3 upvotes 1 month ago

Nanoxidil Serum is discussed as an alternative to minoxidil, with concerns about its availability and suggestions to enhance minoxidil absorption using retinoic acid or microneedling. One user reported improvement with Nanoxidil shampoo but experienced tinnitus and stopped using it.

community Natural protocol doesn’t work !

14 upvotes 3 months ago

Natural treatments for hair loss were ineffective for OP, who saw improvement only after starting minoxidil and finasteride. Users suggest that proven medications like finasteride and minoxidil are more effective than natural remedies.

community Napkin math: are we using 100x more topical finasteride than necessary?

in Finasteride/Dutasteride 4 upvotes 4 months ago

Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.

community Naturally high T (1,100+) causing diffuse thinning while on Dut

22 upvotes 5 months ago

A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

community Do natural remedies actually work or it is nonsense?

in Chat 3 upvotes 5 months ago

Natural remedies may improve hair and scalp health but do not stop hair loss related to DHT or other imbalances. Proven treatments like Minoxidil and Finasteride are recommended for effective results.

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