One-Step Generation of Core–Shell Biomimetic Microspheres Encapsulating Double-Layer Cells Using Microfluidics for Hair Regeneration
January 2023
in “
Biofabrication
”
microfluidic-assisted technology double-layer cell microspheres hair regeneration mouse mesenchymal cells epidermal cells gelatin methacrylate photo-curable catechol-grafted hyaluronic acid GelMA-MSC/HAD-EPC microspheres biocompatibility growth factor release hair follicles dorsal dermis organoid applications microfluidics biomimetic microspheres hair growth mesenchymal cells GelMA hyaluronic acid biocompatible growth factors hair follicle generation skin dermis organoids
Studysummary This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
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