Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia

    March 2020 in “ Frontiers in Bioengineering and Biotechnology ”
    Fengxuan Han, Jiayuan Wang, Luguang Ding, Yuanbin Hu, Wenquan Li, Zhangqin Yuan, Qi Guo, Caihong Zhu, Yu Li, Huan Wang, Zhongliang Zhao, Luanluan Jia, Jiaying Li, Yingkang Yu, Zhang Wei-dong, Genglei Chu, Song Chen, Li Bin
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    TLDR Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
    The document from March 2020 reviews the progress in tissue engineering and regenerative medicine (TERM) in Asia, highlighting the development of novel biomaterials, cell sources, and applications in various tissues. It discusses the use of modified polymers, ceramics, metals, and composite materials for tissue regeneration and the importance of mechanical stimuli in tissue development and repair. The document also covers advancements in 3D printing, cell sheet technology, genome editing, and microfluidics, as well as the use of stem cells, including mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs), in clinical trials for treating various conditions. Despite significant progress, the document concludes that the clinical application of TERM is still limited, indicating more work is needed for broader clinical integration.
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