The Pharmacology of Regenerative Medicine

    July 2013 in “ Pharmacological Reviews
    George J. Christ, Justin M. Saul, Mark E. Furth, Karl‐Erik Andersson
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    TLDR Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
    The document from July 1, 2013, introduced regenerative pharmacology, which merges pharmacological tools with regenerative medicine to repair and replace damaged cells, tissues, and organs. It discussed the potential of this approach to provide curative treatments through targeted drug delivery, orchestrating regenerative responses, and creating functional tissues and organs for implantation. The review highlighted the need for interdisciplinary collaboration, particularly involving pharmacologists, to develop complex compound mixtures for tissue and organ restoration. It cited that 500,000 patients were treated with regenerative medicine products from 1998 to 2011, demonstrating the field's growth and the necessity for further research into regenerative mechanisms and technologies. The document also covered advancements in drug delivery, tissue engineering, scaffold design, and the role of biomaterials in enhancing tissue repair and controlled drug delivery. It examined the treatment of complex organ diseases like bladder disease and Parkinson's Disease, emphasizing the promise of regenerative pharmacology in developing new treatment strategies. The paper concluded by advocating for the application of pharmacological sciences to regenerative medicine and viewing the report as a starting point for future progress in tissue and organ regeneration.
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