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research Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation.

104 citations , July 1994 in “The Journal of Cell Biology”

This study suggests that basonuclin in keratinocytes is likely a regulatory molecule linked to maintaining proliferative capacity and preventing terminal differentiation rather than a cell cycle marker.

Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression

research Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras‐dependent up‐regulation of KGF expression

51 citations , December 2003 in “The FASEB Journal”

This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.

The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

research The Ludwig pattern of androgenetic alopecia is due to a hierarchy of androgen sensitivity within follicular units that leads to selective miniaturization and a reduction in the number of terminal hairs per follicular unit

47 citations , September 2008 in “British Journal of Dermatology”

This study found that women with androgenetic alopecia experience diffuse hair loss due to a decrease in terminal hairs and an increase in vellus hairs per follicular unit.

research Localization of Plasminogen Activator Inhibitor Type 2 (PAI-2) in Hair and Nail: Implications for Terminal Differentiation

42 citations , June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed that PAI-2 is consistently expressed in differentiating cells of murine hair and nail, suggesting it may function as a marker of differentiation and possibly protect against premature cell death.

research Long-term efficacy of topical minoxidil in male pattern baldness

41 citations , March 1987 in “Journal of The American Academy of Dermatology”

This study observed that 2% minoxidil solution was at least as effective as 3% for increasing hair growth and stabilizing bald areas in men with male pattern baldness.

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Community Join

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community Terminal hairs growing in, but derm still says I’m going to go bald in the years to come??

in Chat 5 upvotes 1 year ago

A 30-year-old woman with a history of anemia and low vitamin D experienced hair shedding, which improved after addressing nutrient deficiencies. Despite regrowth of terminal hairs, her dermatologist recommended treatments like minoxidil and spironolactone to prevent future bald spots, but she is cautious due to family history of hormone-related cancers.

community Long-term experiences with minoxidil only

6 upvotes 6 days ago

Minoxidil can help with hair regrowth but stopping it may lead to worse hair loss than before starting. Finasteride is more effective for long-term stability but has potential side effects that some users prefer to avoid.

community Long term 0.25 -0.33mg finasteride dose for maintenance

5 upvotes 1 week ago

The conversation discusses using a low dose of finasteride (0.25-0.33mg) for hair loss maintenance, with some users suggesting alternatives like topical finasteride and addressing sleep issues potentially unrelated to the medication. Suggestions include taking finasteride in the morning, improving sleep hygiene, and considering melatonin.

community Any 1-1.5 mg dutasteride LONG TERM (2+ years) users here? Please, share your experience!

7 upvotes 3 weeks ago

Long-term users of dutasteride, often combined with minoxidil, report mixed results in managing hair loss, with some experiencing side effects like stomach pain and dark circles. Despite increasing dosages, many still face receding hairlines, suggesting genetic factors may play a significant role.

community Long term Fin/Min random shed experience

15 upvotes 9 months ago

The user experienced significant hair shedding while using finasteride and oral minoxidil but found that the shedding eventually stopped, and hair returned to its previous state. They advise patience, continuing medication, and maintaining good nutrition, including Vitamin D.

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Learn

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learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Hydrocortisone

What are the risks of long-term hydrocortisone use on the scalp? Dermatology reviews describe long-term topical corticosteroid use as causing skin thinning, delayed healing, greater infection risk, possible suppression of the body's own cortisol, and rebound flares on stopping — and over-the-counter hydrocortisone labels limit use to about a week without a doctor's direction.

learn Osteopontin

Is Osteopontin safe to use long-term in hair growth products? Osteopontin's long-term safety in hair growth products is not yet established.

learn KY19382

Is KY19382 safe to use long-term, or is it still considered experimental? KY19382 is still considered experimental and lacks long-term safety data.

learn Rapamycin

Is rapamycin safe for long-term use on the scalp, or should it be used in cycles? There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.

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Clinics

1 / 204 results

15
Hair Loss Treatments
Bioheal Természetgyógyászat, HajdiagnosztikaBudapest · HU

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