TLDR Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
The paper "Research Progress of Extracellular Vesicles-Loaded Microneedle Technology" reviews the advancements in using microneedles (MNs) loaded with extracellular vesicles (EVs) for therapeutic and diagnostic applications. MNs are praised for their minimally invasive drug delivery capabilities, and EVs are effective due to their low immunogenicity and cell-specific traits. The combination shows promise in treating conditions like hair loss, spinal cord injury, and diabetic ulcers by enhancing targeted delivery. The review highlights recent advancements, challenges, and future research directions, emphasizing the potential of this innovative approach in regenerative medicine and targeted therapy.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
31 citations,
July 2022 in “Advanced healthcare materials/Advanced Healthcare Materials” A drug-free microneedle patch significantly promotes hair growth and prevents infections.
61 citations,
June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
86 citations,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
4 citations,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
6 citations,
February 2023 in “Biomaterials Research” Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
3 citations,
June 2023 in “MedComm” Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
