Research Progress of Extracellular Vesicles-Loaded Microneedle Technology

The paper "Research Progress of Extracellular Vesicles-Loaded Microneedle Technology" reviews the advancements in using microneedles (MNs) loaded with extracellular vesicles (EVs) for therapeutic and diagnostic applications. MNs are praised for their minimally invasive drug delivery capabilities, and EVs are effective due to their low immunogenicity and cell-specific traits. The combination shows promise in treating conditions like hair loss, spinal cord injury, and diabetic ulcers by enhancing targeted delivery. The review highlights recent advancements, challenges, and future research directions, emphasizing the potential of this innovative approach in regenerative medicine and targeted therapy.