A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations, and Applications

    August 2021 in “ Polymers ”
    Faisal Khaled Aldawood, Abhay Andar, Salil Desai
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    TLDR Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
    The document reviews microneedles, detailing their types, materials, processes, characterizations, and applications. Microneedles have been used in biomedical applications such as drug delivery, vaccination, and extraction of dermal interstitial fluid for glucose and alcohol monitoring. They've been incorporated in dissolvable microneedle array patches for delivering antigens like the Hepatitis B surface antigen and used for intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140. They've also been used to deliver vaccines against polio, Bacillus Calmette-Guérin, and hepatitis C. In terms of hair loss and alopecia, microneedling has been successful in treating alopecia areata and androgenetic alopecia. The document also explores the use of 3D printing in microneedle system manufacturing and the potential of artificial neural networks in the design and manufacturing process.

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    Can we use stamps with triangular needles?

    June 2024, 3 posts
    craggg
    ...36/4/NP168/2613925 2 ], even with titanium-coated tips. If anyone has information on research specific to stimulation and needle shape, please share. tressless.com A Comprehensive Review of Microneedl...

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      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 5 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community What else is good. Besides the big 3.

      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Please stop looking for a natural way to stop your hairloss

      in Chat  247 upvotes 2 years ago
      There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

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