A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations, and Applications

    August 2021 in “ Polymers
    Faisal Khaled Aldawood, Abhay Andar, Salil Desai
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    TLDR Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
    The document reviews microneedles, detailing their types, materials, processes, characterizations, and applications. Microneedles have been used in biomedical applications such as drug delivery, vaccination, and extraction of dermal interstitial fluid for glucose and alcohol monitoring. They've been incorporated in dissolvable microneedle array patches for delivering antigens like the Hepatitis B surface antigen and used for intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140. They've also been used to deliver vaccines against polio, Bacillus Calmette-Guérin, and hepatitis C. In terms of hair loss and alopecia, microneedling has been successful in treating alopecia areata and androgenetic alopecia. The document also explores the use of 3D printing in microneedle system manufacturing and the potential of artificial neural networks in the design and manufacturing process.

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      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 4 months ago
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