Novel Treatment Modalities for Hair Loss

    July 2018 in “ Elsevier eBooks ”
    Aron G. Nusbaum, Suchismita Paul
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    TLDR New hair loss treatments show promise, but more research is needed to confirm their effectiveness.
    The 2019 document reviewed novel treatments for hair loss, including platelet-rich plasma (PRP), low-level laser/light therapy (LLLT), mesotherapy, microneedling, and adipose-derived stem cell (ADSC) therapy. PRP showed a "clinically important difference" in hair growth in 40.6% to 54.7% of subjects in a trial with 64 patients, but results varied across studies. LLLT was found to increase hair density and had an excellent safety profile, with one study involving 110 male patients. Mesotherapy, particularly with dutasteride and vitamins, showed positive results, but also side effects like scalp abscesses and patchy alopecia. Microneedling combined with minoxidil was more effective than minoxidil alone in a study with 100 patients. ADSC therapy showed potential in promoting hair growth, with one trial of 20 patients indicating increased hair diameter and density. However, the document emphasized the need for larger, more controlled studies to fully assess the effectiveness of these treatments.
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      community What else is good. Besides the big 3.

      in Chat  34 upvotes 3 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  829 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Any New Findings or Interesting Research?

      in Research/Science  24 upvotes 11 months ago
      The conversation is about seeking new research on hair loss treatments beyond the commonly known ones like Minoxidil and Finasteride. Additions to the list of treatments include topical caffeine, alfatradiol, fluridil, stemoxydine, and upcoming treatments like TDM-105795 and verteporfin.

      community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

      in Research/Science  3 upvotes 1 year ago
      The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

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