TLDR Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
This document from 2006 discusses the use of finasteride, a 5-alpha-reductase inhibitor, in the treatment of benign prostatic hyperplasia and male pattern hair loss. It also explores the impact of finasteride on neuroactive steroid levels and behavior, as well as its potential uses beyond its current clinical applications. The document highlights preclinical research involving animal models of anxiety and depression and clinical investigations with findings relevant to depression, seizure susceptibility, sexual behavior, and alcohol-related behaviors. Finasteride has been useful in the treatment of benign prostatic hyperplasia and androgenetic alopecia, but side effects have been reported in a small percentage of patients.View this study on onlinelibrary.wiley.com →
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.
Finasteride reduces alcohol withdrawal effects, especially in female mice.
Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
Finasteride effectively treats male pattern baldness, improving hair growth and density.
Finasteride can slow hair loss and promote growth in postmenopausal women.
Low-dose finasteride effectively reduces hirsutism without serious side-effects.
Finasteride blocks progesterone's effect on absence seizures in rats.
All three treatments reduce hirsutism, but spironolactone works best long-term.
Progesterone boosts alcohol's effect on brain, finasteride counters it.
Finasteride for hair loss may cause depression, affecting sleep and relationships.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
Diane 35 plus finasteride is more effective for treating hirsutism.
Flutamide reduces hair growth better but has more side effects.
Finasteride effectively treats male hair loss, improving growth and density.
Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
Both drugs lower DHT levels, with GI198745 being more effective.
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
Finasteride affects prostate weights and pituitary activity differently with age.
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
Four-amino acid part makes enzyme sensitive to finasteride.
Finasteride effectively treats BPH, but needs more trials to understand potential.
Finasteride safely lowers DHT levels without affecting testosterone.
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
Finasteride doesn't affect hormone levels in normal men.