Safety of 5α-Reductase Inhibitors and Spironolactone in Breast Cancer Patients Receiving Endocrine Therapies

    Raquel Rozner, Azael Freites-Martínez, Jerry Shapiro … Mario E. Lacouture
    Studysummary In this review, researchers found no evidence of interactions between 5α-reductase inhibitors or spironolactone and endocrine therapies for breast cancer, with no consistent changes in estrogen levels or increased breast cancer risk associated with spironolactone usage.
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    1. Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Dermatology · 2017
    2. Lack of Effect of Spironolactone on Hair Shaft Diameter in Hirsute Females Postgraduate medical journal · 1989