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Glossary Endocrine Therapy-Induced Alopecia

hair loss caused by treatments that alter hormone levels

Endocrine Therapy-Induced Alopecia, also known as Hormone Therapy-Induced Alopecia, refers to hair loss that occurs as a side effect of treatments that alter hormone levels, commonly used in managing cancers like breast or prostate cancer. These therapies, such as tamoxifen or aromatase inhibitors, disrupt the normal hormonal balance, leading to thinning hair or baldness.

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Research

5 / 1000+ results

research Endocrine Therapy–Induced Alopecia in Patients With Breast Cancer

67 citations , April 2018 in “JAMA Dermatology”

This study found that endocrine therapy for breast cancer is associated with a pattern of hair loss similar to androgenetic alopecia, negatively impacting quality of life despite mild severity.

research Minoxidil for Endocrine Therapy–Induced Alopecia in Women With Breast Cancer—Saint Agatha’s Blessing?

9 citations , April 2018 in “JAMA Dermatology”

This abstract provided no research findings as it contains only website navigation and service information.

research Approaches to management of endocrine therapy–induced alopecia in breast cancer patients

1 citations , February 2025 in “Supportive Care in Cancer”

Safe treatments like minoxidil and spironolactone can help manage hair loss in breast cancer patients without increasing cancer risk.

Interim Analysis of Platelet-Rich Plasma Treatment for Endocrine Therapy-Induced Alopecia and Permanent Chemotherapy-Induced Alopecia in Breast Cancer Patients: A Randomized Controlled Trial

research 51895 Interim Analysis of Platelet-Rich Plasma (PRP) Treatment for Endocrine Therapy-Induced Alopecia (EIA) and Permanent Chemotherapy-Induced Alopecia (pCIA) in Breast Cancer Patients: A Randomized Controlled Trial

September 2024 in “Journal of the American Academy of Dermatology”

This review discusses the limited evidence on the efficacy of platelet-rich plasma for treating endocrine therapy-induced and permanent chemotherapy-induced alopecia and reports no new clinical results.

research 0478 Outcomes of oral dutasteride and oral minoxidil for treating endocrine therapy-induced alopecia from breast cancer treatment: A case series

July 2025 in “Journal of Investigative Dermatology”

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Community Join

5 / 135 results

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Anyone else super depressed cause of hairloss?

in Finasteride/Dutasteride 185 upvotes 1 year ago

A 20-year-old is dealing with hair loss, using finasteride and oral minoxidil, and considering dutasteride. Others suggest treatments like dutasteride, hair transplants, therapy, and lifestyle changes to boost confidence and mental health.

community Finally, some real breakthroughs. A comparison of the two leading baldness treatments: PP405 versus ABS-201

106 upvotes 10 months ago

PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

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Learn

7 / 801 results

learn Overview

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.
Is applying Estradiol directly to the scalp effective for hormone-related hair thinning? Applying Estradiol directly to the scalp may help with hormone-related hair thinning.
Why is Estradiol used to treat hair loss in women and transgender people undergoing hormone therapy? Estradiol helps treat hair loss by balancing hormones and supporting hair follicle health.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib helps regrow hair by targeting the autoimmune response in alopecia areata.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

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Clinics

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13
Hair Loss Treatments
DECON (Diabetes & Endocrine Center of Nevada) SparksSparks, NV · US

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