TLDR Topical minoxidil improves hair loss in 80% of women with breast cancer undergoing endocrine therapy.
The document, from 5 years ago, discussed a study by Freites-Martinez et al. on endocrine therapy-induced alopecia (EIA) in women with breast cancer, involving 112 patients. It found that 67% of alopecia cases were attributed to aromatase inhibitors and 33% to tamoxifen. The hair loss significantly affected the patients' quality of life. However, topical minoxidil improved alopecia in 80% of treated patients. The document also explored the role of estrogens and androgens in hair growth and loss, and the effectiveness of topical minoxidil in treating female androgenetic alopecia. It concluded that while hair loss from chemotherapy and endocrine therapy couldn't be completely prevented, it could be managed with treatments like scalp cooling and topical minoxidil.
Cited in this study
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34 citations
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November 2013 in “Breast Cancer Research and Treatment” Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.
48 citations
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September 2013 in “Oncologist” Endocrine therapies for cancer significantly increase the risk of hair loss.
52 citations
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May 2013 in “Supportive Care in Cancer” Scalp cooling significantly reduces hair loss in chemotherapy patients.
68 citations
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November 2012 in “Annals of Oncology” Some breast cancer chemotherapy can cause permanent hair loss.
57 citations
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June 2011 in “The American Journal of Dermatopathology” Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.
28 citations
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January 2007 in “Dermatology” Chemotherapy can cause rapid, extensive hair loss, with patterns varying between individuals.
159 citations
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July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
149 citations
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June 2002 in “British Journal of Dermatology” Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.