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GlossaryTamoxifen

medication used to treat and prevent breast cancer

Tamoxifen, also known by brand names like Nolvadex and Soltamox, is a medication primarily used to treat and prevent breast cancer. It works by binding to estrogen receptors, thereby blocking the effects of estrogen on breast tissue, which can slow or stop the growth of hormone receptor-positive breast cancer cells.

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Postoperative Chemotherapy and Tamoxifen Compared with Tamoxifen Alone in the Treatment of Positive-Node Breast Cancer Patients Aged 50 Years and Older with Tumors Responsive to Tamoxifen: Results from the National Surgical Adjuvant Breast and Bowel Project B-16

research Postoperative Chemotherapy and Tamoxifen Compared with Tamoxifen Alone in the Treatment of Positive-Node Breast Cancer Patients Aged 50 Years and Older with Tumors Responsive to Tamoxifen: Results from the National Surgical Adjuvant Breast and Bowel Project B-16

279 citations , June 1990 in “Journal of Clinical Oncology”

Adding chemotherapy to tamoxifen improves survival for older breast cancer patients with positive nodes.

research Tamoxifen for Flutamide/Finasteride-Induced Gynecomastia

49 citations , December 1997 in “Urology”

Tamoxifen effectively treats gynecomastia without causing impotence.

Analysis of Quantitative Changes in Hair Growth During Treatment With Chemotherapy or Tamoxifen in Patients With Breast Cancer: A Cohort Study

research Analysis of Quantitative Changes in Hair Growth During Treatment With Chemotherapy or Tamoxifen in Patients With Breast Cancer: A Cohort Study

24 citations , November 2013 in “British Journal of Dermatology”

Chemotherapy causes hair loss starting soon after treatment begins and recovers about 3 months after ending, while tamoxifen does not significantly affect hair growth.

research Clinical Case Notes: Tamoxifen Optic Neuropathy

23 citations , February 2004 in “Clinical and Experimental Ophthalmology”

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

research Tamoxifen-Induced Total Alopecia

19 citations , June 2001 in “Annals of Internal Medicine”

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

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community Successfuly combating gynocomastia with an extremly low dose of topical Tamoxifen

in Treatment 9 upvotes 2 months ago

Using a low dose of topical Tamoxifen effectively reduces gynecomastia caused by finasteride, with minimal side effects. The solution involves mixing Tamoxifen with ethanol and propylene glycol, applied daily to the chest.

community Gyno & testoterone level

in Finasteride 282 upvotes 1 year ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 14 upvotes 4 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

community How to keep taking finasteride after getting gynecomastia as a side effect (Full guide and 4 year search complete).

in Finasteride/Dutasteride 52 upvotes 3 years ago

User experienced gynecomastia from finasteride and found a solution using liposomal topical finasteride. This method minimizes side effects and is effective for hair loss treatment.

community Does RU58841 potentially cause cancer?

in Research/Science 3 months ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

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