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Glossary Tamoxifen

medication used to treat and prevent breast cancer

Tamoxifen, also known by brand names like Nolvadex and Soltamox, is a medication primarily used to treat and prevent breast cancer. It works by binding to estrogen receptors, thereby blocking the effects of estrogen on breast tissue, which can slow or stop the growth of hormone receptor-positive breast cancer cells.

Related Terms

Endocrine Therapy-Induced Alopecia

Research

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research Postoperative chemotherapy and tamoxifen compared with tamoxifen alone in the treatment of positive-node breast cancer patients aged 50 years and older with tumors responsive to tamoxifen: results from the National Surgical Adjuvant Breast and Bowel Project B-16.

279 citations , June 1990 in “Journal of Clinical Oncology”

The study found that for positive-node breast cancer patients aged 50 and older, adding chemotherapy to tamoxifen significantly improved disease-free survival compared to tamoxifen alone.

research Tamoxifen for flutamide/finasteride-induced gynecomastia

49 citations , December 1997 in “Urology”

This study found that low-dose tamoxifen may effectively treat painful gynecomastia in patients receiving flutamide and finasteride for advanced prostate cancer.

research Analysis of quantitative changes in hair growth during treatment with chemotherapy or tamoxifen in patients with breast cancer: a cohort study

24 citations , November 2013 in “British Journal of Dermatology”

This study found that chemotherapy in female breast cancer patients caused significant early hair loss, which began to recover three months after completion, whereas tamoxifen did not affect hair growth.

research Clinical Case Notes. Tamoxifen optic neuropathy

23 citations , February 2004 in “Clinical and Experimental Ophthalmology”

This case report describes a 68-year-old woman with metastatic breast cancer who experienced significant improvement in visual acuity after stopping tamoxifen, which was associated with bilateral optic neuropathies.

research Tamoxifen-Induced Total Alopecia

19 citations , June 2001 in “Annals of Internal Medicine”

This case report describes total alopecia in a 53-year-old woman after 13 months of tamoxifen treatment for breast cancer, with normal hair distribution maintained elsewhere.

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Community Join

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community Successfuly combating gynocomastia with an extremly low dose of topical Tamoxifen

10 upvotes 1 year ago

Using a low dose of topical Tamoxifen effectively reduces gynecomastia caused by finasteride, with minimal side effects. The solution involves mixing Tamoxifen with ethanol and propylene glycol, applied daily to the chest.

community Dutasteride or treatment and TRT/PEDs

1 upvotes 1 month ago

A user experienced hair thinning after using tamoxifen and bupropion and is now using topical dutasteride, alfatradiol, melatonin, adenosine, and specific shampoos for improvement. They are considering using steroids and are seeking advice on whether combining oral dutasteride with TRT/PEDs would affect hair health, with mixed opinions on the impact of testosterone and DHT on hair loss.

community Want to maximize hair regrowth and maintenance while avoiding gyno

11 upvotes 1 week ago

To minimize the risk of gynecomastia while maximizing hair regrowth, some suggest using finasteride six times a week and dutasteride once, while others recommend using raloxifene or tamoxifen. Concerns about gynecomastia are common, with some users experiencing flare-ups despite low estrogen levels, and others advising caution and considering surgery if necessary.

community Got Gynecomastia from Dutasteride, now what?

7 upvotes 1 month ago

The user experienced gynecomastia after switching from finasteride to dutasteride and is considering stopping dutasteride or having surgery to remove the gland. They are advised to stop dutasteride, consider surgery, and explore medications like raloxifene or tamoxifen to manage symptoms.

community Gyno & testoterone level

in Finasteride 282 upvotes 2 years ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

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