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    Did you mean TUNEL assay?
    Glossary TUNEL assay

    detects DNA fragmentation in cells undergoing apoptosis

    The TUNEL assay, or Terminal deoxynucleotidyl transferase dUTP nick end labeling, is a laboratory technique used to detect DNA fragmentation resulting from apoptotic signaling. It works by labeling the ends of broken DNA strands, allowing researchers to identify and quantify cells undergoing programmed cell death, which can be important in studies of diseases like cancer or conditions affecting hair follicles, such as alopecia.

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    Research 30 of 1000+

    1. Detection of Bim and Puma in mouse hair follicles using immunofluorescence and TUNEL assay double staining Biotechnic & histochemistry · 2015 · 3 citations
    2. YAP and TAZ are essential for basal and squamous cell carcinoma initiation EMBO Reports · 2018 · 76 citations
    3. A primer for studying cell cycle dynamics of the human hair follicle Experimental Dermatology · 2016 · 38 citations
    4. Apoptotic cell death in canine hair follicle. PubMed · 2005 · 5 citations
    5. Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture Experimental Dermatology · 2009 · 132 citations
    6. Therapeutic small extracellular vesicles from key human stem and immune cellular sources: A review Journal of Biomedical Research · 2026
    7. The patch assay reconstitutes mature hair follicles by culture-expanded human cells Regenerative Medicine · 2017 · 11 citations
    8. Undifferentiated connective tissue disease presenting with vascular pattern of renal amyloidosis with carpel tunnel syndrome: A case report International Journal of Case Reports and Images · 2014
    9. “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    10. Human hair follicle organ culture: theory, application and perspectives Experimental Dermatology · 2015 · 130 citations
    11. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles PLOS Biology · 2018 · 68 citations
    12. Comparisons of mouse models for hair follicle reconstitution Experimental Dermatology · 2011 · 24 citations
    13. Assessment of markers expressed in human hair follicles according to different skin regions Advances in Clinical and Experimental Medicine · 2018 · 6 citations
    14. 883 Hair follicle bulb developed as 3D scaffold free microtissue Journal of Investigative Dermatology · 2017
    15. Hair follicle stem cell cultures reveal self‐organizing plasticity of stem cells and their progeny The EMBO Journal · 2016 · 61 citations
    16. Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering Journal of Dermatological Science · 2013 · 57 citations
    17. Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays International Journal of Molecular Sciences · 2022 · 9 citations
    18. The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury Cell Metabolism · 2025
    19. Effect of minoxidil formulations on human scalp skin xenotransplants on SCID mice – a novel pre‐clinical in vivo assay for androgenetic alopecia research Experimental Dermatology · 2022
    20. Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol-Analogs 1998 · 53 citations
    21. Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/Fas L-Mediated Apoptotic Signaling PloS one · 2014 · 29 citations
    22. An investigation of apoptosis in androgenetic alopecia. PubMed · 2003 · 2 citations
    23. Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis Reproductive Biology and Endocrinology · 2019 · 48 citations
    24. Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐2 FEBS Open Bio · 2021 · 29 citations
    25. Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi PLoS neglected tropical diseases · 2017 · 41 citations
    26. Characterization of spironolactone and metabolites derivatized using Girard's reagent P using mass spectrometry and ion mobility spectrometry Rapid Communications in Mass Spectrometry · 2024 · 4 citations
    27. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005 · 205 citations
    28. MoS2 Nanoclusters-based biomaterials for disease- impaired wound therapy Applied Materials Today · 2020 · 15 citations
    29. Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters BMC Genomics · 2018 · 16 citations
    30. 0877 Activated wound phenotype and microbial dysbiosis are driven by AhR suppression in hidradenitis suppurativa tunnels Journal of Investigative Dermatology · 2025