Advances in Platelet Rich Plasma-Derived Extracellular Vesicles for Regenerative Medicine: A Systematic-Narrative Review

August 2023 in “ International Journal of Molecular Sciences ”

Eduardo Anitua, María Troya, Juan Manuel Falcón‐Pérez, Silvia López-Sarrio, Esperanza González, Mohammad Hamdan Alkhraisat

Platelet Rich Plasma-Derived Extracellular Vesicles PRP-EVs hair loss hair growth dermal papilla cells cell proliferation cell migration wound healing PRP EVs

Studysummary This review compiles evidence from 20 relevant studies and suggests that platelet-rich plasma-derived extracellular vesicles represent a promising therapeutic option in regenerative medicine, although the authors emphasize the need for standardized protocols due to inconsistencies across studies.

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research Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells

5 citations , October 2021 in “PubMed”

This study found that exosomes derived from human adipose stem cells significantly enhanced the proliferation and migration of dermal papilla cells compared to those from platelet-rich plasma, suggesting potential benefits for hair loss treatment.

research Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives

29 citations , December 2019 in “Transfusion and Apheresis Science”

This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.